Researchers at Case Western Reserve University School of Medicine have discovered how specific protein regions contribute to ...

GPR6 is an orphan G protein-coupled receptor ... specific drugs that can reduce its activity. The experiments revealed a lipid-like molecule occupying the orthosteric ligand-binding pocket.

"Finding the exact binding site on the receptor offers the perfect template for developing ketamine-like drugs that could be ...

The next steps for PAGER involve exploring different applications, simplifying its structure, and enhancing its ability to operate autonomously – such as automatically delivering drugs upon receptor ...

It is hard to overestimate the importance of antibodies in the frameworks of biotechnology and pharmaceutical industries.

The apelin receptor (APJR) is a drug target for cardiovascular and metabolic health. Here, authors reveal how ligand binding, receptor dimerization, and G protein coupling cooperate to regulate ...

(OTCQB: BIXT) (the “Company”), a clinical stage biotechnology company developing oral and intravenous drugs to treat viral diseases, fibrosis, stroke, dementia, and Alzheimer's disease, announced its ...

G protein-coupled receptors (GPCRs), crucial for diverse physiological responses, have traditionally been investigated in ...

The binding between a biosimilar and its target antigen (and Fc receptors) is regarded as a key indicator of its efficacy. ACROBiosystems has designed high-quality target antigen proteins and Fc ...

G-protein coupled receptors regulate ... accomplished by synthesizing drugs which have similar structures to natural ligands to generate new molecules capable of binding to GPCRs and stimulating ...

They block pain signals in the brain, binding to opioid receptors in the brain, spinal cord, and elsewhere. “Basically, it’s, as the name suggests, a synthetic drug made in the laboratory.

The discovery, published Dec. 13 in Nature Communications, paves the way for new diagnostic tests to guide treatment and could also help drug ... a DNA-binding section of the androgen receptor ...