If our genes are so similar, what really makes a eukaryote different from a prokaryote, or a human from E. coli? The answer lies in the difference in gene expression and regulation used.

Next, we turn to the regulation of genes ... Interestingly, in eukaryotes, the default state of gene expression is "off" rather than "on," as in prokaryotes. Why is this the case?

A research team at KAIST has identified the core gene expression networks regulated ... enzymes serve as vital secondary ...

Constitutive splicing is where every intron in the primary RNA transcript is removed as transcription progresses along the gene. Alternative splicing is where exon or intron skipping can occur.

For the first time, researchers have developed a genome-scale way to map the regulatory role of transcription factors, proteins that play a key role in gene expression and determining a plant's ...

They inserted these two sequences upstream of a reporter gene and used a colorimetric assay to determine whether the proteins repressed the reporter’s expression based on ... tunable as well as ...

Sterols, such as cholesterol in our bodies or ergosterol in yeast cells, are among the most abundant lipids in eukaryotic cells ... elongation enzymes during gene expression, findings that ...

Our research program focuses on two primary points of control: transcription of messenger RNA (mRNA) and post-transcriptional regulation of mRNAs by microRNAs (miRNAs). A critical control point for ...

A research team has identified the core gene ... expression in animal cells. Inositol phosphate metabolites produced by inositol metabolism enzymes serve as vital secondary messengers in ...

The course explores gene regulation in eukaryotes from nuclear organisation to cytosolic ... along with the role of RNA processing and post-transcriptional regulation in gene expression, and their ...

They seek to understand how cells modulate gene expression by modulating chromatin and DNA organization. Fred Hutch researchers have done pioneering work in the areas of gene regulation, chromatin ...