Disrupting the G-loop cycle causes transcriptome dysregulation and genome instability, revealing key role in cell survival ...

A research team led by Prof. Cao Xiaofeng from the Institute of Genetics and Developmental Biology (IGDB) of the Chinese Academy of Sciences has uncovered a key translational regulatory mechanism ...

It binds to protein kinases and membrane‐bound receptors in a regulated fashion. Interestingly, RACK1 is also a constituent of the eukaryotic ribosome, and a recent cryo‐electron microscopy study ...

RNA gene scissors (CRISPR-Cas13) are gaining significant attention as a next-generation gene therapy with fewer side effects.

Further advances in the genetic analysis of variation in gene expression will contribute to our understanding of transcriptional regulation and will provide models for studying other quantitative ...

In this study, we developed a standardized toolkit utilizing an engineered CRISPR/Cas9 system that enables customizable gene regulation in mammalian cells ... A construct for constitutive SEAP ...