Disrupting the G-loop cycle causes transcriptome dysregulation and genome instability, revealing key role in cell survival ...

A research team led by Prof. Cao Xiaofeng from the Institute of Genetics and Developmental Biology (IGDB) of the Chinese Academy of Sciences has uncovered a key translational regulatory mechanism ...

RNA gene scissors (CRISPR-Cas13) are gaining significant attention as a next-generation gene therapy with fewer side effects.

This study provides useful information on the impact of Lamin A/C knockdown on gene expression using RNA-Seq analysis. In addition, the impact of Lamin A/C knockdown on telomere dynamics is explored ...

Chinese researchers have developed a technology that sheds light on how the three-dimensional (3D) organization of plant genomes influences gene expression—especially in photosynthesis.

A research team has identified the core gene ... expression in animal cells. Inositol phosphate metabolites produced by inositol metabolism enzymes serve as vital secondary messengers in ...

Gene regulation is essential for life and controlled by ... Non-regulatory and regulatory DNA contain motifs to which transcription factors may bind. In prokaryotes, gene expression requires a stretch ...

For the first time, researchers have developed a genome-scale way to map the regulatory role of transcription factors, proteins that play a key role in gene expression and determining a plant's ...

Department of Molecular and Cellular Biology, University of Geneva, Geneva, Switzerland Genomes of higher eukaryotes encode a large tubulin ... their “identity” when it comes to tubulin gene ...

The genome of a eukaryotic organism is comprised of a supra-molecular ... high-order chromatin organizations in deciphering transcriptional regulation of gene expression under environmental stress (4D ...