“There is a significant need to bring more targeted, well-tolerated, effective treatment options that address the pathophysiology of gMG disease,” said UCB’s chief medical officer, Iris Loew ...
How Does Vyvgart Work in gMG? gMG is an autoimmune disease where the immune system mistakenly damages the connections between your nerves and muscles. This weakens your muscles and affects how ...
4,5 B cells are central to the pathogenesis of gMG. The disease is thought to be primarily driven by pathogenic CD19+ plasmablasts and plasma cells that target critical proteins in the ...
The mean disease duration was about 8 years ... “For someone living with gMG, a 1 to 2-point improvement on MG-ADL may be the difference between normal eating and frequent choking on food ...
Some research has suggested that a high percentage of juvenile gMG patients may require hospitalization in an ICU throughout the course of their disease. Nipocalimab was designed to block the IgG ...
Just a few months into a new launch in chronic inflammatory demyelinating polyneuropathy (CIDP), agrenx’ Vyvgart is already making headway in the rare disease space, just one of the long-term growt | ...
“We are committed to developing innovations for autoantibody-driven neurological diseases, like gMG, with the aim of transforming the lives of people living with these conditions.” Earlier ...
COUR Pharmaceuticals CHICAGO, Oct. 30, 2024 (GLOBE NEWSWIRE) -- COUR Pharmaceuticals, a clinical-stage biotechnology company focused on the development of first-in-class, disease-modifying ...
"UPLIZNA targets CD19+ pre-B cells, mature B-cells and some plasmablasts, which are drivers of the disease. The clinically significant results from the MINT trial further strengthen the growing ...