This sophisticated genomic mechanism is estimated to have developed from 650 to 700 million years ago, 150 million years ...

Life depends on genes being switched on and off at exactly the right time. Even the simplest living organisms do this, but ...

Imprinting is yet another process involved in eukaryotic gene regulation; this process involves the silencing of one of the two alleles of a gene for a cell's entire life span. Imprinting affects ...

An elegant screening strategy unveils a molecular actor that connects widespread changes in mRNA processing with a nutrient-sensing protein modification.

Gene regulation refers to the mechanisms that act to induce or repress the expression of a gene. These include structural and chemical changes to the genetic material, binding of proteins to ...

The study, published in Nucleic Acids Research, opens the door to more precise exploration of RNA-based gene regulation and could one day help scientists better understand and even control gene ...

Constitutive splicing is where every intron in the primary RNA transcript is removed as transcription progresses along the gene. Alternative splicing is where exon or intron skipping can occur.

Even the simplest living organisms do this, but usually over short distances across the DNA sequence, with the on/off switch typically right next to a gene. This basic form of genomic regulation ...