These intracellular signaling pathways, also called signal transduction cascades, typically amplify the message, producing multiple intracellular signals for every one receptor that is bound.

The p38 MAPK regulates intracellular signaling pathways in response to environmental stress. Its inhibition blocks the production of inflammation-causing cytokines, such as IL-1β and TNF-α ...

Disease-causing mutations in the signaling protein BMP4 impair its secretion, but only when it is made as a homodimer.

Mitochondria, traditionally acclaimed as the powerhouses of eukaryotic cells due to their role in ATP synthesis, are ...

Dr. Pushkar Lele received a National Institute of General Medical Sciences research grant to investigate how bacteria sense their mechanical environment.