TMC207 is a first-in-class anti-TB diarylquinoline (also named R207910 or the 'J' compound) with activity against drug-sensitive and drug-resistant TB. TMC207 inhibits the proton pump of ...

Oral anticoagulants (OACs) are medications commonly used in patients with atrial fibrillation and other cardiovascular conditions. Both warfarin and direct oral anticoagulants are susceptible to ...

Oxazolines and oxazoles have high antitubercular activity with Min. Inhibitory Concn. (MIC) of 0.7812-25.0μg/mL (3.21-100.3μM), against two strains of Mycobacterium tuberculosis sensitive to ...