Conclusion . The results of our analysis suggest that INH prophylaxis reduces the risk of TB by 59% among children ≤ 15 years of age, excluding a subset of young children on whom INH was ...

Introduction. Although isoniazid (INH) is a key component of the current tuberculosis management strategy, but its hepatotoxic potentiality remains a significant clinical problem (Yew and Leung, 2006; ...

Over the last 12 years, drug-resistant TB was isolated in 9.5% (n = 1,598) of people diagnosed with active TB disease and whose isolates were subjected to susceptibility testing. Of these, 83.2% (n = ...

Drug-induced liver injury cases are increasing, with common medications and supplements posing hidden dangers, especially for vulnerable populations.

Traditional treatments for hereditary angioedema have involved replacing C1-Inh using infusions of this protein from donor blood, Ritchie says. Patients can use these infusions to treat attacks, ...

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Combining alcohol and antibiotics can increase your chance of developing side effects. It’s best to wait until you’re done with your antibiotic course before consuming alcohol.

TMC207 is a first-in-class anti-TB diarylquinoline (also named R207910 or the 'J' compound) with activity against drug-sensitive and drug-resistant TB. TMC207 inhibits the proton pump of ...

Background: A description is given of a major outbreak of isoniazid monoresistant tuberculosis (TB) chiefly in north London, including prisons. The earliest case was diagnosed in 1995 with most cases ...