A deep-learning model trained on human data reveals that promoter mutations may explain a significant portion of unsolved ...

G6Pase gene promoter activity responded to glucose in this H4IIE cell line in the ... The PCR primers, covering the −1309 to +68 region of G6Pase gene (transcriptional start as +1), were ...

Investigating how mutations in tumors alter DNA’s 3D structure—and subsequently, regulatory sequences called enhancers—can ...

Insulin Gene Expression . Humans, ... The 5' and 3' 8-bp flanking regions of the insulin promoter A boxes (shown in their natural order along the promoter) were compared with human A boxes.

The growing incidence of infectious diseases, cancer, and chronic illnesses has substantially increased the demand for ...

A recent study reveals a link between blood type and stroke risk, particularly for early-onset strokes. Individuals with type ...

Using quantitative proteomics, the authors uncover that ZMAT3 knockout leads to upregulation of HKDC1, a gene linked to mitochondrial respiration, and that ZMAT3 suppresses HKDC1 expression by ...

Regeneration, the ability to heal damaged or lost tissues, is both an everyday and a real-life superpower. Health research ...

This valuable study identifies asymmetric dimethylarginine (ADMA) histones as potential determinants of the initial genomic binding of Rhino, a Drosophila-specific chromatin protein essential for ...

Modifications in proteins after they are synthesized (post-translational) are changes that play a fundamental role in cell ...

Up to half of patients with Crohn's disease, an inflammatory bowel disease, develop a complication called fibrosis, where the ...

A study by Professor Yinhua Huang’s team at China Agricultural University has for the first time constructed a “graph-based pan-genome” for chickens, ...