Elevated lipoprotein(a) concentrations are associated with atherosclerotic cardiovascular disease. The safety and efficacy of lepodisiran, an extended-duration, small interfering RNA targeting hepa ...

Technological advances in the design and delivery of mRNA have catalysed the rapid development of mRNA COVID-19 vaccines by ...

The team's findings were published in Science.. How little RNA snippets silence genes. Both microRNAs and the related class of small interfering RNAs (siRNAs) are small snippets of RNA—just 21 ...

AbbVie Inc. (NYSE:ABBV) is one of the best stocks to buy for beginners now. In mid-May, AbbVie and ADARx Pharmaceuticals ...

RNA interference (RNAi) is a natural mechanism for controlling gene expression. 1 It is also commonly referred to as post-transcriptional gene silencing (PTGS). 2 Common to plants, animals, fungi, and ...

Small RNA molecules, such as microRNAs (miRNAs) and small interfering RNAs (siRNAs), are critical regulators that orchestrate ...

Replacing some chemical pesticides with potentially safer, more environmentally benign alternatives is a significant ...

Small interfering RNA "is a promising genetic medicine approach for silencing disease-causing genes, but challenges still remain in targeting and delivering siRNA effectively," Jonathon Sedgwick, ...

A new possibility for managing cardiovascular disease through RNA interference (RNAi) gene therapies. As cardiovascular diseases continue to be the leading cause of death globally, this technology ...

About The Study: Zerlasiran, a small-interfering RNA targeting hepatic synthesis of apolipoprotein(a), was well-tolerated and reduced time-averaged lipoprotein(a) concentration by more than 80% ...