Understanding how cells transform into specialized types during human development is a central challenge in biology. This complex process, known as cell differentiation, holds the key to understanding ...
The vertebrate protein Dead end maintains primordial germ cell fate by inhibiting somatic differentiation. Developmental cell 43:704-715.
It has been suggested that DNA methylation analysis of genomic regions highly methylated in somatic cells in comparison to germ cells can help identify somatic cell contamination in sperm samples (9, ...
Primordial germ cells (PGCs) are the bipotential precursors of mature gametes ... The critical processes required for PGCs to integrate and respond to signals from the somatic environment in gonads ...
2016; Luong et al., 2020). Follicles are complex aggregations comprising germ cells and various somatic cells, and the regulation of folliculogenesis not only relies on the complex signal ...
Testicular GCT have low rates of somatic mutations, though have been shown to be associated with a gain of chromosome 7, a portion of which encodes c-MET. When hepatocyte growth factor (HGF) binds to ...
Understanding how cells transform into specialized types during human development is a central challenge in biology. This complex process, known as cell differentiation, holds the key to understanding ...
Human health is strongly intertwined with the health of the microbiome. A large number of studies have shown that the human ...