Animals, from worms and sponges to jellyfish and whales, contain anywhere from a few thousand to tens of trillions of nearly genetically identical cells. Depending on the organism, these cells arrange ...

Germline gene therapy and somatic gene therapy are two quite different proposals, and the legitimate concerns and risks of the former should not be used to stall progress on the latter.

The cells that make up non-germline tissues and organs are called somatic cells, which are not passed on to the next ...

Scientific organizations recently called for a 10-year ban on human germline editing. But will we ever be ready? And how ...

Pedro C. Barata, MD, MSc, discusses a typical process for an oncologist to patients who are newly diagnosed with metastatic ...

A dedicated Abu Dhabi cancer centre has carried out more than 25,000 treatments since opening to the public two years ago ...

Within each treatment arm, most treatment emergent adverse event incidence rates were generally similar overall and between patients with germline and somatic mutations. The most frequent any grade ...

Mismatch repair (MMR) germline alterations are enriched among patients with uveal melanoma (UM), according to a study ...

HRD tumors because of BRCA loss are uniquely sensitized to PARP inhibition because of a synthetic lethal interaction between BRCA and PARP. 56, 57 HRD tumors manifest a characteristic and identifiable ...