The activation of the coagulation cascade yields thrombin that converts ... Gobel also discusses the FDA-approved unlabeled uses of tranexamic acid for the management of bleeding in DIC ...

Heparan sulfate (HS), dermatan sulfate (DS), and heparin are natural glycosaminoglycans (GAG), which are linear polysaccharides, heterogeneous in both sequence and length. 1 GAGs carry out many ...

Tranexamic Acid for Patients With Traumatic Brain Injury A Randomized, Double-Blinded, Placebo-Controlled Trial. Surakrant Yutthakasemsunt; Warawut Kittiwatanagul; Parnumas Piyavechvirat; Bandit ...

Anatomic pathology studies performed over 150 years ago revealed that excessive activation of coagulation occurs in the setting of inflammation. However, it has taken over a century since these ...

Interference With Coagulation Cascade as a Novel Approach to Counteract Cisplatin-Induced Acute Tubular Necrosis; ... Rivaroxaban induces mucosal healing in a rat model of trinitrobenzene sulfonic ...

The 1980 eruption cycle made Mount St. Helens one of the most famous volcanoes in the Cascades. But it is far from the only volcano in the range.

Tranexamic acid (TXA) is a lysine-analog antifibrinolytic agent that inhibits fibrinolysis by reversibly binding to lysine receptor sites on plasminogen and plasmin, thereby disrupting their ...

Angiopoietin-2 (Ang-2), a principal modulator of endothelial dysfunction, exhibits a robust correlation with the risk of disseminated intravascular coagulation (DIC) (OR >5) and death, whereas ...

We present an efficient, pseudotelescopic synthesis of β-amino acids via the Arndt-Eistert homologation of α-amino acids using a flow reactor cascade. Our system utilizes flow generation of ...

This work reports on a simple and feasible colorimetric immunoassay with signal amplification for sensitive determination of prostate-specific antigen (PSA, used as a model) at an ultralow ...