FMS-like tyrosine kinase 3 (FLT3) mutations represent some of the most pivotal genetic alterations in acute myeloid leukemia (AML), influencing ...

Currently, five tyrosine kinase inhibitors (TKIs—imatinib ... The ASC4FIRST trial has confirmed that tolerability and molecular response with asciminib are superior to those with both imatinib and the ...

Computational Biophysics and CADD Group, Computational and Mathematical Biology Centre (CMBC), Translational Health Science and Technology Institute (THSTI), Faridabad 121001, India Delhi ...

Tyrosine kinase inhibitors, such as gefitinib (Iressa ™, ZD1839), block the EGFR. As a result, there is inhibition of cellular proliferation, promotion of apoptosis, and inhibition of anti ...

Laboratory of Chemistry for Functionalized Surfaces, Division of Environmental Chemistry, Institute for Chemical Research, Kyoto University, Gokasho, Uji, Kyoto 611-0011, Japan ...