Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells. However, to be effective, the new gene must make it into a cell's nucleus. The ...

Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells. However, to be effective, the new gene must make it into a cell's nucleus. The ...

Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal ...

When it comes to neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and certain forms of dementia, ...

The new workflow was adapted from an enzymatic DNA tagging technology, DNA-TAG, previously developed in the Devaraj lab. In ...

Researchers have linked overactive protein quality control to nuclear pore damage and neurodegenerative disease pathology.

Lurking among them is a “giant” virus, a genetic behemoth that blurs the line between the living and the inanimate. When this ...

A study suggests overactive VCP may contribute to ALS nerve damage by disrupting nuclear pore proteins in genetic ALS.

Discover how Laverdia CA1 (verdinexor) treats canine lymphoma. Learn about the mechanism of action, handling precautions, and ...

Specifically, scientists have worked with “exosomes” — tiny biological mail trucks that stem cells dispatch to tell neighbors ...