A study has found that an ancient protein motif that binds to nucleic acids is functionally "ambidextrous." This means that ...

In a new study published in Cell Reports, researchers at the University of Freiburg reveal how a disordered protein segment helps connect two key steps of gene expression: the reading of genes and the ...

By creating a more true-to-life representation of DNA's environment, researchers have discovered that strand separation may take more mechanical force than the field previously believed.

An elegant screening strategy unveils a molecular actor that connects widespread changes in mRNA processing with a nutrient-sensing protein modification.

We have shown that PEI-mannose polymers compact DNA into nanoshell-like particles, which can load proteins as well. Here we show that these DNA containers are uniquely versatile for scavenging ...

They have expanded beyond small molecules aimed at blocking enzyme activity by mimicking a substrate to encompass larger compounds that manipulate protein ... the DNA or RNA that encode problem ...

Of course, it also holds up previous research that has demonstrated how lipids and proteins cross-talk in other membranes inside cells. “Most labs study the roles of DNA, RNA, and proteins in ...

Extending this discovery recently in Cell, Flynn and colleagues showed that glycoRNAs form highly organized clusters with RNA-binding proteins on the cell surface. These clusters appear to ...

In this review, we have discussed the advances in blood-based biomarkers in PDAC, such as DNA (mutations and methylations), RNA, protein biomarkers and circulating tumor cells (CTC) over the last ...

Bacteria have evolved several different mechanisms to target protein complexes, membrane vesicles and DNA to specific positions within the cell. This versatility allows bacteria to establish the ...

Protein–RNA complexation is an important step for the regulation of numerous biological processes. Water present at the interface of a protein–RNA complex plays a critical role in guiding its ...