The current methods to control RNA functions in living conditions are limited. The new RNA-controlling strategy presented in this study involves utilizing 5-formylcytidine (f5C)-directed base ...

The ability to control mammalian genes in a synergistic mode using synthetic transcription factors is highly desirable in fields of tissue engineering, stem cell reprogramming and fundamental research ...

In humans, the TRPA1 gene is located on chromosome 8, band q21.11, and consists of 68,761 base pairs and 29 exons according to the updated data on NCBI. Notably, the TRPA1 gene is not limited to ...

A 17-gene genomic prostate score as a predictor of adverse pathology for men on active surveillance. Zachary Kornberg , Matthew R. Cooperberg , Janet E. Cowan , Jeffry Simko , June M. Chan , Imelda ...

(10), we propose an active–reactive coordinated voltage regulation strategy for a rural distribution network based on the vector-weighted average optimization or INFO algorithm. The INFO algorithm ...

This pattern mirrors the gene transcription structures established by CTCF and RNAPII in the human host, enhancing the efficiency of gene transcription and regulation (Tang et al, 2015). Notably, we ...

A newly identified mechanism shows that the NIPBL-MAU2-glucocorticoid receptor (GR) ternary complex modulates gene expression by facilitating cohesin loading and chromatin structure alteration.