which involves the inhibition of CD28-mediated PI3K/AKT/mTOR costimulatory signaling. Kao et al. provide insight into the metabolic requirements of IL-17A-producing γδ T cells, offering an ...

The adaptive immune system allows T- and B-cells to generate an enormously diverse response to different pathogens. Both the naive T- and B-cell receptor repertoire are generated by interaction ...

where they undergo positive and negative selection to produce a nonself-binding T-cell antigen receptor, and emerge as naive, single, positive T cells. After encountering antigen in the periphery ...

Welcome to Zymeworks first-quarter 2025 results conference call and webcast. (Operator Instructions) I would now like to turn the conference over to Shrinal Inamdar, Senior Director of Investor ...

Yescarta – a CD19-directed genetically modified autologous T-cell immunotherapy investigated in the ZUMA-1 trial – is the first chimeric antigen receptor (CAR) T-cell therapy recommended for ...