DNA replication is the biological process by which an exact copy ... Each of the two strands of the DNA molecule acts as a template for the synthesis of a complementary strand. Related Subjects.

Mitochondrial DNA polymerases use different mechanisms for strand separation during replication. Here, the authors reveal the cryo-EM structures of yeast Mip1, identifying key structural elements ...

DNA replication is a fundamental process required of all cell types (1–3).Replicative polymerases (Pol), such as the leading-strand polymeraseε (Polε) and lagging-strand Polδ, synthesize DNA with ...

Your DNA is continually damaged by sources both inside and outside your body. One especially severe form of damage called a ...

Disrupting the G-loop cycle causes transcriptome dysregulation and genome instability, revealing key role in cell survival and homeostasis.

Experiments with tools designed to detect DNA damage reveal unique and conserved features of telomeres in cancer cells.

Not all DNA looks like the familiar twisted ladder. Sometimes, parts of our genetic code fold into unusual shapes. One such structure, the G-quadruplex (G4), looks like a knot. These knots can play ...

A new study in Nature Plants reveals that DNA double-strand break repair (DSBR) pathways help prevent gene transfer from organelles to the nucleus in plants. Disruption of DSBR increases the risk of ...

Viruses are entirely dependent on their hosts to reproduce. They ransack living cells for parts and energy and hijack the ...

All the latest science news on dna replication from Phys.org ... This process is "semiconservative" in that each strand of the original double-stranded DNA molecule serves as template for the ...

Parallel-stranded (ps) DNA characterized by its sugar–phosphate backbones pointing in the same direction represents an alternative pairing system to antiparallel-stranded (aps) DNA with the potential ...

Dynamic DNA structures are controlled through toehold-based strand displacement, a method in which a DNA or RNA strand can bind to a single-stranded extension, cause branch migration, and result in ...