A new study reveals that neurons in the brainstem respond very differently to acute versus chronic pain, potentially ...

The ancient wandering womb theory suggested that many ailments in women were caused by the uterus becoming dislodged and ...

Neural processing unts (NPUs) are the latest chips you might find in smartphones and laptops — but what are they ard why are they so important?

Located on the ventral end of the neural tube, the floor plate acts as one such signaling center to pattern the dorsal/ventral axis by secreting the morphogen Sonic Hedgehog (SHH). Here, we present a ...

Furthermore, many pNSCs that migrate out of the neural tube can differentiate into mature neurons and ... and can be isolated from mouse embryonic limb, postnatal lung, tail, dorsal root ganglia and ...

we report that the end of the neural crest period is regulated by retinoic acid synthesized in the dorsal neural tube. Inhibition of retinoic acid signaling in the neural tube prevents the normal ...

The central nervous system of the cephalochordate amphioxus consists of a dorsal neural tube with an anterior brain. Two decades of gene expression analyses in developing amphioxus embryos have shown ...

Lurie Children’s Hospital of Chicago, Chicago, IL, United States 2 Department of Ophthalmology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States During vertebrate ...

Neural tube (NT) formation in the spinal region of the mammalian embryo involves a wave of “zippering” that passes down the elongating spinal axis, uniting the neural fold tips in the dorsal midline.

are required for completion of neural tube closure. By genetically ablating the cytoskeletal regulators Rac1 or Cdc42 in the dorsal neuroepithelium, or in the surface ectoderm, we show that these ...

Here we show that DNA methyltransferase 3B (DNMT3B) is responsible for the loss of competence of dorsal neural tube cells to generate emigrating neural crest cells. DNMT3B knockdown results in ...