Disrupting the G-loop cycle causes transcriptome dysregulation and genome instability, revealing key role in cell survival ...

Not all DNA looks like the familiar twisted ladder. Sometimes, parts of our genetic code fold into unusual shapes. One such ...

A team led by Professor Won Do Heo from the Department of Biological Sciences, KAIST, has developed a pioneering technology ...

The ratio of nuclei to cell volume is a well-controlled parameter in eukaryotic cells. This important study now ... production capacity and why it excels as a host for heterologous expression. This ...

RNA gene scissors (CRISPR-Cas13) are gaining significant attention as a next-generation gene therapy with fewer side effects.

Further advances in the genetic analysis of variation in gene expression will contribute to our understanding of transcriptional regulation and will provide models for studying other quantitative ...

In this study, we developed a standardized toolkit utilizing an engineered CRISPR/Cas9 system that enables customizable gene regulation in mammalian cells ... A construct for constitutive SEAP ...

Key Laboratory of Biomedical Polymers of Ministry of Education, College of Chemistry and Molecular Sciences, The Institute of Molecular Medicine, Wuhan University People’s Hospital, Hubei Province Key ...

Temporal and spatial control of gene expression in the mouse can be achieved using binary transgenic systems, in which gene expression is controlled by the interaction of an effector protein ...