Disrupting the G-loop cycle causes transcriptome dysregulation and genome instability, revealing key role in cell survival ...

Not all DNA looks like the familiar twisted ladder. Sometimes, parts of our genetic code fold into unusual shapes. One such ...

RNA gene scissors (CRISPR-Cas13) are gaining significant attention as a next-generation gene therapy with fewer side effects.

In this study, we developed a standardized toolkit utilizing an engineered CRISPR/Cas9 system that enables customizable gene regulation in mammalian cells ... A construct for constitutive SEAP ...

Key Laboratory of Biomedical Polymers of Ministry of Education, College of Chemistry and Molecular Sciences, The Institute of Molecular Medicine, Wuhan University People’s Hospital, Hubei Province Key ...

Transposable elements contribute to evolution, but their own diversification remains incompletely understood. Here, insect ...

This study provides useful information on the impact of Lamin A/C knockdown on gene expression using RNA-Seq analysis. In addition, the impact of Lamin A/C knockdown on telomere dynamics is explored ...

Chinese researchers have developed a technology that sheds light on how the three-dimensional (3D) organization of plant ...

It moves through the DNA and creates specific loops in the genetic material which determine the architecture of the genome and gene expression. Some mutations in the genes of the cohesion complex ...

Indeed, the NPC is emerging as an important regulator of gene expression through its influence ... pre-dates the emergence of the major modern eukaryotic lineages (reviewed in Ref.

A comparative genomic approach elucidated the composition of the BCAT gene family in durum wheat. Here we demonstrate a tissue and developmental stage specificity of BCATs regulation in ... support ...