Leukocyte migration into and through tissues is fundamental to normal physiology, immunopathology and host defence. Leukocyte entry into the central nervous system (CNS) is restricted, in part ...

The diverse leukocyte infiltrate in atherosclerotic mouse aortas was recently analyzed in 9 single-cell RNA sequencing and 2 mass cytometry studies. In a comprehensive meta-analysis, we confirm 4 ...

The lesions can have various possible appearances, such as: Papules (bumps) Nodules (larger lumps or masses) Ulcers (open sores) Leukemia cutis results when abnormal white blood cells (called ...

To get to the site of inflammation, leukocytes must first adhere to and traverse the blood-vessel wall, ... CD44 association with VLA-4 in T cell extravasation. Immunity 20, ...

The different components of blood—oxygen, sugars, hormones, proteins, circulating lipids, but also suspended extracellular vesicles of different sizes (exosomes, microvesicles and apoptotic ...

A study initiated by a University of Arizona Comprehensive Cancer Center physician-scientist defined for the first time how loss of the Y chromosome in male immune cells negatively affects immune ...

Multiple myeloma is considered incurable, but a third of patients in a Johnson & Johnson clinical trial have lived without detectable cancer for years after facing certain death.

White blood cells (leukocytes). These help fight infections and aid in the immune process. Platelets (thrombocytes). These help to control bleeding. Where are blood cells made? Blood cells are made in ...

The capacity of immune cells to migrate between the blood and tissues/organs; to interact with other cell types within the body and to adjust behavior and morphology upon environmental changes, are ...

Patients with suspected or confirmed systemic lupus erythematosuss ("lupus" or SLE) undergo laboratory tests (blood tests) for multiple reasons. Physicians and other health care professionals test ...

Background: Given a potential risk of extravasation with vesicants and irritants, central venous catheters (CVCs), such as port-a-cath or peripherally inserted central catheters, are commonly utilized ...

Nanoparticles have been extensively used to deliver therapeutic drugs to tumor tissues through the extravasation of a leaky vessel via enhanced permeation and retention effect (EPR, passive targeting) ...