Supraphysiological expression of α-Gal A activity maintained for over a year in longest treated patient as of data cutoff date ~~ Stable ...

A new technique brings CRISPR-mediated gene editing together with spatial transcriptomics and imaging to study the ...

Fluoxetine exposure during early auditory development drove 91 gene expression changes in the brainstem, reduced the stability of mature neural circuits, an ...

Validated, tissue-specific library enables customisable and controllable liver-targeted gene expression with high specificity and minimal off-target activity in muscle tissue ...

Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells.

Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells. However, to be effective, the new gene must make it into a cell's nucleus.

The new workflow was adapted from an enzymatic DNA tagging technology, DNA-TAG, previously developed in the Devaraj lab. In ...

Over the past two decades, researchers have learned that DNA inside the cell nucleus naturally folds into a network of ...

Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells. However, to be effective, the new gene must make it into a cell's nucleus. The ...

Epigenetic modifications such as DNA methylation play a key role in regulating gene expression. Emerging evidence suggests ...

Life Biosciences tests ER-100, a gene therapy that aims to restore vision by rejuvenating damaged retinal neurons.

Psoriasis is a common inflammatory skin disease linked to several long-term health conditions, such as heart disease, ...