The study of germline stem cells in the nematode Caenorhabditis elegans (C. elegans) provides valuable insights into the mechanisms of stem cell regulation and differentiation. C. elegans serves ...
The nucleus of a germline stem cell undergoes two divisions, firstly separating homologous chromosomes and secondly separating chromatids. Haploid gametes contain 23 single chromosomes.
How do somatic stem cells control germline stem cell (GSC) biology? How do somatic cells regulate restoration of GSCs following stress? How are soma-germline interactions disrupted during ...
They can also differentiate into cells from unrelated germline lineages (a process known ... the functional components of the haematopoietic stem cell (HSC) niche that support HSC homeostasis ...
View Full Profile. Learn about our Editorial Policies. In the freshwater polyp Hydra vulgaris, a single population of stem cells is responsible for both gamete production and the sea anemone’s ...
Modifying genes in a human embryo is one way to accomplish this, and speakers at the meeting also discussed a different form of germline engineering, one that involves modifying the stem cells ...
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In an international collaboration, researchers have made an important breakthrough in the therapeutic delivery of microRNAs ...
Dr. Singh's laboratory studies post-transcriptional gene regulation. The focus is on how RNA-binding proteins control molecular processes during male and female germline stem cell differentiation.
Since stem cells have the ability to turn into various other types of cells they can be useful for treating and understanding disease. Researchers can use stem cells in laboratories to test new ...
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Genetic germline variations influence expression of cancer cell genes, finds studyThe findings, published in the journal Cell Reports Medicine, show that specific germline structural variations represent potential candidates for cancer genetic testing, including those involving ...
In sickle-cell disease scientists must fix the stem cells that go on to make blood ... able to reach those cells more easily. The lure of germline editing, though, is unlikely to go away.
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