Researchers have uncovered another piece of the Parkinson’s disease puzzle, identifying that particular immune cells are ...

Our cells carry out hundreds of thousands of important functions every day, all of which are carefully orchestrated at a ...

Some, known as dendritic cells, take up proteins from foreign pathogens, chop them up into peptides called antigens, and display them on their surface. Another group, known as helper T cells, inspects ...

The research indicates that reprogrammed T helper cells adopt characteristics of a new T helper cell type while preserving some of their original traits, making them “super powerful and potent ...

Amgen and CytomX Therapeutics have kicked a phase 1 T-cell engager to the curb, axing the asset after assessing the clinical data and their pipeline priorities. CytomX signaled the EGFRxCD3 ...

On February 13, Allogene Therapeutics published new long-term follow-up data on cemacabtagene ansegedleucel, showing the investigative allogeneic chimeric antigen receptor (CAR) T-cell therapy ...

“Today, we are excited to announce the next phase of Xilio’s tumor-activation platform with multiple internal masked T cell engager programs, as well as a multi-program collaboration with AbbVie,” ...

Identifying this organelle as a potential target to improve the performance of T-cells in the TME, the team set out to investigate the stress response of the Golgi to this environment and identify ...

Scientists at St. Jude Children’s Research Hospital have shown that nutrient availability and organelle biology affect the development of tissue-resident memory T cells. “We are excited to ...

This study, led by Dr. Panpan Jiang and collaborators at Tongji Medical College, explores the critical role of the Dedicator of Cytokinesis 8 (DOCK8) gene in the differentiation of helper T cells ...

They found that a specific type of immune cell, called T follicular helper cells, indirectly controls the anti-influenza response. These helper cells often "see" the wrong parts of the virus ...