Opening day for the Chicago White Sox will mark the start of their attempt to rebuild the team after an MLB record-setting 121 losses last year.

The Chicago White Sox win total over/under is 54.5, according to the FanDuel Sportsbook, which is the lowest number of all 30 MLB teams. At 59.5, the Colorado Rockies are the only other team below 60. The Los Angeles Dodgers lead the league at 105.5 and have a significant lead over the Atlanta Braves in second at 92.5.

Now, Opening Day is here, and so is Will Venable's debut as the White Sox manager. Here's how we project the Opening Day lineup for the 2025 Chicago White Sox. Vaughn, Robert, Benintendi and Sosa were regular contributors to the Sox's offense last year.