Subtype selective dopamine receptor ligands have long been sought after as therapeutic and/or imaging agents for the treatment and monitoring of neurologic disorders. We report herein on a combined ...

The release of the “feel-good” chemicals dopamine, serotonin, endorphins, and oxytocin are tied to specific lifestyle, exercise, and dietary choices. Here’s what triggers each one.

In this work, we carried out neurochemical and behavioral analysis of zebrafish (Danio rerio) treated with rotenone, an agent used to chemically induce a syndrome resembling Parkinson’s disease (PD).

Background Recently, symptoms similar to addictive drug withdrawal have been reported in a structured longitudinal study of patients with idiopathic Parkinson's Disease (PD) withdrawing from dopamine ...

MOUNTAIN VIEW, Calif., June 03, 2025--Alto Neuroscience, Inc. ("Alto") (NYSE: ANRO), a clinical-stage biopharmaceutical company focused on the development of novel precision medicines for ...

Alto Neuroscience Announces Acquisition of Novel Dopamine Agonist Combination Product Candidate, Adding Late-Stage Readout in Treatment Resistant Depression Within Current Cash Runway – ALTO-207 ...

Long-term use of cocaine and heroin disrupts dopamine signaling in the brain, depleting receptors and diminishing the effects of non-drug stimuli, such as music, to trigger pleasure.

'Dopamine is the main player in our sense of purpose,' says the famed neuroscientist. Speaking on the 'This Past Weekend' podcast, he explains how to reset your dopamine system for renewed motivation.

Andrew Huberman explains why motivation fades, what dopamine actually does, and how to train your brain to stay in the hunt. This is key for getting your motivation back.

Dopamine agonists are considered first-line treatment of RLS. Dopamine precursors like levodopa are also widely used for this disorder. In May 2005, ropinirole became the first Food and Drug ...

Dopamine signaling in the brain is a complex process, with many mechanisms in place to accelerate or slow down dopamine’s effects. When dopamine is released from nerve cells, its efficient removal to ...

According to the French guidelines, very severe cases of RLS require treatment with low-dose dopamine agonists, such as pramipexole, rotigotine, or ropinirole. These drugs may also help reduce ...