Approved eight months ago for a certain class of patients with both hemophilia A or B, Pfizer’s Hympavzi has now shown its ...

Elevated lipoprotein(a) concentrations are associated with atherosclerotic cardiovascular disease. The safety and efficacy of lepodisiran, an extended-duration, small interfering RNA targeting hepa ...

The team's findings were published in Science.. How little RNA snippets silence genes. Both microRNAs and the related class of small interfering RNAs (siRNAs) are small snippets of RNA—just 21 ...

SAN ANTONIO, June 26, 2025--bioAffinity scientists present breakthrough research on using siRNAs to knock down two receptors ...

Technological advances in the design and delivery of mRNA have catalysed the rapid development of mRNA COVID-19 vaccines by ...

Innovent Biologics is pivoting to R&D and oncology growth in China, but high valuation and risks temper upside. Read why ...

RNA interference (RNAi) is a natural mechanism for controlling gene expression. 1 It is also commonly referred to as post-transcriptional gene silencing (PTGS). 2 Common to plants, animals, fungi, and ...

About The Study: Zerlasiran, a small-interfering RNA targeting hepatic synthesis of apolipoprotein(a), was well-tolerated and reduced time-averaged lipoprotein(a) concentration by more than 80% ...

Xalnesiran is an investigational small interfering RNA that silences multiple transcripts from the HBV genome. Ruzotolimod, also investigational, is a toll-like receptor 7 agonist selectively ...

A new possibility for managing cardiovascular disease through RNA interference (RNAi) gene therapies. As cardiovascular diseases continue to be the leading cause of death globally, this technology ...

Small interfering RNA "is a promising genetic medicine approach for silencing disease-causing genes, but challenges still remain in targeting and delivering siRNA effectively," Jonathon Sedgwick, ...

Small RNA molecules, such as microRNAs (miRNAs) and small interfering RNAs (siRNAs), are critical regulators that orchestrate ...