A new modelling study reveals that only 7% of carbapenem-resistant Gram-negative (CRGN) bacterial infections in eight LMICs ...

Tetracyclines impair cellular function by targeting ribosomes. Here, the authors demonstrate that tigecycline impairs T cell function by selectively inhibiting mitochondrial protein synthesis and ...

Even with more restrictive assumptions, the analysis still showed a substantial treatment gap, with only 14.2% of patients ...

There have been 8,064 reported cases of whooping cough in the U.S. so far this year, according to the latest data from the Centers for Disease Control and Prevention. There were 3,835 cases at the ...

A study published April 17 by BMC Infectious Diseases found increased incidents of Acinetobacter baumannii and carbapenem-resistant A. baumannii infections between 2018 to 2022. A. baumannii is a ...

Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China University of Chinese Academy of Science, Beijing 100049, China ...

The clinical burden of carbapenem-resistant Acinetobacter baumannii has worsened across U.S. hospitals in recent years, according to a study published April 17 in BMC Infectious Diseases.

Since tigecycline can be one of the rare treatment options in some multidrug-resistant Gram-negative bacteria (e.g. Acinetobacter baumannii), further studies with higher doses of tigecycline are ...

Class A enzymes include β-lactamases that are active against penicillins and cephalosporins as well as extended-spectrum β-lactamases that are also active against penicillins and cephalosporins ...

Saccharin disrupted iron and sulfur metabolism pathways in A. baumannii, crippling the pathogen’s ability to scavenge essential metals—a vulnerability absent in traditional antibiotics.