See Figure 1 for a depiction of normal hemostasis. The activation of the coagulation cascade yields thrombin that converts fibrinogen to fibrin; the stable fibrin clot being the final product of ...

Heparan sulfate (HS), dermatan sulfate (DS), and heparin are natural glycosaminoglycans (GAG), which are linear polysaccharides, heterogeneous in both sequence and length. 1 GAGs carry out many ...

Tranexamic Acid for Patients With Traumatic Brain Injury A Randomized, Double-Blinded, Placebo-Controlled Trial. Surakrant Yutthakasemsunt; Warawut Kittiwatanagul; Parnumas Piyavechvirat; Bandit ...

Anatomic pathology studies performed over 150 years ago revealed that excessive activation of coagulation occurs in the setting of inflammation. However, it has taken over a century since these ...

Interference With Coagulation Cascade as a Novel Approach to Counteract Cisplatin-Induced Acute Tubular Necrosis; ... Rivaroxaban induces mucosal healing in a rat model of trinitrobenzene sulfonic ...

But it is far from the only volcano in the range. From southern British Columbia to Northern California, the Cascade Range comprises an 800-mile chain of volcanoes. So, how did this volcanic lands ...

Introduction Traumatic brain injury is a leading cause of death and disability. Tranexamic acid, an antifibrinolytic agent, holds the potential for managing intracranial hemorrhages secondary to ...

Angiopoietin-2 (Ang-2), a principal modulator of endothelial dysfunction, exhibits a robust correlation with the risk of disseminated intravascular coagulation (DIC) (OR >5) and death, whereas ...

Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 5 Akademik Kuhar Street, 02660 Kyiv, Ukraine Taras Shevchenko National University of Kyiv, 60 Volodymyrska Street, 01601 Kyiv, ...

This work reports on a simple and feasible colorimetric immunoassay with signal amplification for sensitive determination of prostate-specific antigen (PSA, used as a model) at an ultralow ...