A new imaging breakthrough combines ultrasound and light-based techniques to generate vivid 3D images that show both tissue ...

The new workflow was adapted from an enzymatic DNA tagging technology, DNA-TAG, previously developed in the Devaraj lab. In ...

Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells. However, to be effective, the new gene must make it into a cell's nucleus. The ...

Oral vaccines promise painless, needle-free protection—but the human gut evolved to destroy exactly what vaccines are made of ...

Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells. However, to be effective ...

They discovered that an ongoing viral infection causes a brief but striking shift in the availability of nutrients in the ...

As we age, our cells don’t just wear down—they reorganize. Researchers found that cells actively remodel a key structure called the endoplasmic reticulum, reducing protein-producing regions while ...

Researchers show that loss of the SPRTN enzyme lets DNA–protein crosslinks accumulate, leak DNA into the cytoplasm, activate ...

Lurking among them is a “giant” virus, a genetic behemoth that blurs the line between the living and the inanimate. When this ...

In a quiet freshwater pond in Ibaraki Prefecture near Tokyo, researchers have pulled from the water a microscopic giant that ...

DNA, though tightly packed in the nucleus, is constantly threatened by damage from metabolism and external stressors. One particularly severe form of DNA damage is the so-called DNA–protein crosslinks ...

While the concept is well established and several RNAi drugs have reached the clinic, their effectiveness has often been limited by the challenge of delivering fragile RNA molecules intact to the ...