Post-transcriptional regulation is the control of gene expression at the RNA level. It occurs once the RNA polymerase has been attached to the gene's promoter and is synthesizing the nucleotide sequence.

Jul 31, 2022 · Post-transcriptional regulation can occur at any stage after transcription, including RNA splicing, nuclear shuttling, and RNA stability. Once RNA is transcribed, it must be processed to create a mature RNA that is ready to be translated.

The recent discovery of reversible mRNA methylation has opened a new realm of post-transcriptional gene regulation in eukaryotes. The identification and functional characterization of proteins that specifically recognize RNA N 6 -methyladenosine (m 6 A) unveiled it as a modificatio …

Feb 16, 2024 · Post-transcriptional regulation is not only limited to the alternative splicing of genes but involves a myriad of other processes that influence the stability or function of gene products.

Controls on the initiation of gene transcription are the predominant form of regulation for most genes. But other controls can act later in the pathway from DNA to protein to modulate the amount of gene product that is made.

May 23, 2014 · We discuss the regulatory mechanisms that function at the level of mRNA splicing, mRNA polyadenylation, mRNA stability and protein translation, and outline how these mechanisms control the...

Authoritative and up-to-date, Post-Transcriptional Gene Regulation, Third Edition serves as a versatile resource for researchers studying post-transcriptional regulation by both introducing the most recent techniques and providing a comprehensive guide to their implementation.

Post-transcriptional regulation of gene expression plays important roles in diverse cellular processes such as development, metabolism and cancer progression.

Post-transcriptional regulation is the fundamental step in the expression of genes that systematically processes transcribed immature mRNA into the mature one. From previous and newly emerging evidence, altered post-transcriptional regulation can be considered as one of the contributing factors in neurodegenerative diseases.

Jul 1, 2024 · Among the different layers regulating gene expression, the post-transcriptional gene regulation is an essential biological process that has gained interest in recent years because of its implication in many diseases.