Down’s Syndrome, also known as Trisomy 21, is a genetic condition caused by the presence of an extra copy of chromosome 21. This extra genetic material affects the way a baby develops and leads to a combination of physical features, developmental delays, and sometimes health problems. list of soft markers for Down’s syndrome (Trisomy 21) seen on prenatal ultrasound: 1. Increased nuchal translucency (first trimester) 2. Thickened nuchal fold (second trimester) 3. Echogenic intracardiac focus (EIF
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