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The CBC differential is a clue to the diagnosis 1. High blasts. Big red flag for possible acute leukemia 2. High lymphocytes or smudge cells. Seen in chronic lymphocytic leukemia 3. High basophils. Suggestive of chronic myeloid leukemia 4. High nucleated red blood cells. Suggestive of myelofibrosis or marrow infiltration
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1. High blasts on CBC. Big red flag for possible acute leukemia 2. High lymphocytes or smudge cells on CBC. Suggestive of chronic lymphocytic leukemia 3. High basophils on CBC. Strongly suggestive of chronic myeloid leukemia 4. Nucleated red blood cells on CBC. Suggests myelofibrosis, infiltration of cancer in bone marrow
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